Renal function in β-thalassemia major receiving desferal versus deferasirox
نویسندگان
چکیده
منابع مشابه
Immunological evaluation of β-thalassemia major patients receiving oral iron chelator deferasirox.
OBJECTIVE To determine the immune abnormalities and occurrence of infections in transfusion-dependent β-thalassemia major patients receiving oral iron chelator deferasirox (DFX). STUDY DESIGN An observational study. PLACE AND DURATION OF STUDY Hematology Clinics, King Khalid University Hospital, Riyadh, Saudi Arabia, from July to December 2010. METHODOLOGY Seventeen patients with β-thalas...
متن کاملDeferiprone or deferasirox for cardiac siderosis in beta-thalassemia major.
We read with interest the article by Pepe et al. wherein the authors retrospectively compared cardiac iron burden measured by T2* magnetic resonance imaging (MRI) in three groups of beta-thalassemia major patients treated with desferrioxamine, deferiprone, or deferasirox monotherapy for more than one year. The mean global heart T2* value was significantly higher in the deferiprone compared to t...
متن کاملCorrelation of Serum Ferritin Level with Cardiac Function in β-Thalassemia Major
Background: The most important problem in regular transfusion dependent β-thalassemia major is cardiac dysfunction due to iron deposition in it. The aim of this study was to evaluate correlation between serum ferritin levels and cardiac function in β-thalassemia major in Mofid Hospital. Materials and Methods: There were 112 β-thalassemia patients with a mean age of 13.55± 6.12 years, of whom 49...
متن کاملThe Relation between Left Ventricular Function and Serum Ferritin in Major Β-Thalassemia
Abstract Objective Cardiac dysfunction is a major cause of death in patients with beta thalassemia. In these patients, repeated blood transfusion, ineffective erythropoiesis and increased gastrointestinal iron absorption lead to iron overload in the body and this induced heart failure. Left ventricular ejection fraction was measured in major beta thalassemia (β-Th) patients to detect the rela...
متن کاملEvaluation of the Relationship between Serum Ferritin Level and Renal Function in Patients with Thalassemia Major
Background and Aim: Serum ferritin in patients with thalassemia major is an indicator of iron overload, which is the main cause of damage to various organs of the body in patients with thalassemia major. The aim of this study was to investigate the relationship between serum ferritin level and renal function in thalassemia major patients. Materials and Methods: This descriptive and cross-sectio...
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ژورنال
عنوان ژورنال: Journal of Renal Injury Prevention
سال: 2017
ISSN: 2345-2781
DOI: 10.15171/jrip.2018.37